Can this be done with a pressure cooker/ instant pot?

Follow up on cooking this in the instant pot. I followed the recipe exactly as written except I decided to quarter my chuck roast (2.5 lbs) into large chunks. I found a lot of variations on cooking times for chuck roast in an instant pot and went with high pressure cooking for 90 minutes. I then let it release pressure naturally. The meat was SO incredibly tender it was falling apart as I was picking it out to shred. It was a thing of beauty. After that, I finished as written in the recipe with my addition of raisins, and splashes of balsamic vinegar and Worcestershire sauce. Things to note: The strands of meat ended up being too short due to me cutting it in chunks, so I probably would only halve it or not cut it at all. Also, I think the cooking time could be cut back. I'll try again with less time and see how it works!

Did you try this in your instant pot? I just got one for christmas and would love to do it in my pressure cooker.

Definitely! The cooking time will vary though; think of how you'd braise a beef roast or make beef stew in your cooker for a guideline.