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Hmm. I am not a stuffed mushroom expert, but 45 minutes at 375 degrees does seem like a lot of heat. One comment below the recipe stated that the mushrooms did dry out a little and another said that broiling them at the end browned the cheese a little better than baking. Why not check every ten or 15 minutes? Maybe taste one if you think it looks done. I'm sure the type of oven (gas/electric) is also a factor.