If I don't have any grating cheese at all, I will top pasta with bread crumbs fried in olive oil and salted, as per Italian peasants. It gives a nice savory pop.
I think it will very much depend on what you are making. Grana padano is the same family, but the taste will never come close to a good Parmesan. Pecorino is an entirely different taste, but contributes to a dish in its own way.
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