I cook it at 20 minutes per lb. Start at 325F and raise the temperature to 350 for the last hour. It's also a good idea to cover the breast with foil and remove the foil for the last hour. Works every time for me.
A good rule is 13-15 mins per pound which translates to about 4.5 hours. But if its stuffed it will take longer. And 160° is ideal temp to pull the turkey at. It will carry over to 165°+
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Works every time for me.