I'm a big soup girl, so I use them for a sunchoke soup. I've got one of my sunchoke recipes here on food52: http://www.food52.com/recipes/3051_sunchoke_lemongrass_and_leek_soup. And I agree with what fozziebayer says - very good substitute for potatoes.
Anything you would do with potatoes, you can do with sunchokes. I like to toss in olive oil, s&p, and roast or crisp cook in a pan with some oil a la homefries.
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In North Carolina (probably elsewhere too) they make a spicy and sweet pickle with them that I've been trying to replicate for years.