We like to use a round domed loaf for Muffuletta. It leaves room for being more extravagant with the fillings. ;) We pull the insides out of the bread and line both top and bottom with the olive salad before layering the cold cuts, cheese and veggies. It's a little harder to weight down, but it is doable.
Traditionally it's an Italian bread shaped into a round flat loaf. You could use regular Italian bread but I'd suggest you remove a little of the innards so that you have the crisp outer shell and the inside of the sandwich isn't too doughy or soggy.
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