How many calories in one slice of My New Roots Life-Changing Loaf of Bread?

That links looks about right. You have to figure about double a regular slice of bread due to all the nuts and such.

http://www.myfitnesspal.com/food/calories/my-new-roots-life-changing-loaf-of-bread-107095279

Which is 120C/oz. For all practical purpose, it's high in calorie, both high in fat and fiber.