Thanks. I just went ahead and baked it. I couldn't bear the thought of squeezing another bag of key limes! The texture is slightly different, but it tastes fine.
Depends on the recipe, I think. There are recipes that use whole eggs on just the yolks. Here's one: http://www.foodnetwork.com/recipes/emeril-lagasse/key-lime-pie-recipe.html
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What recipe are you using?