pierino is a trusted source on General Cooking and Tough Love.
They are two different herbs. You could use both in combination (or individually) but neither is really a substitute for the other.
HalfPint is a trusted home cook.
Epazote has a fragrant and flavor that's closer to oregano. I would try Mexican oregano as a sub.
I recommend looking for epazote in dried form. Try looking at a hispanic market--they'll be sure to have it. I live in the middle of nowhere, TN, and I can find it without too much fuss. It's also called herba sancti maria or wormseed.
Cynthia is a trusted source on Bread/Baking.
Thanks for the aliases, pb!
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