Can I use Panko in hamburgers?

Just made meatballs with panko and an egg. My daughter thought they had simmered for hours they were so soft, and 'Melting' (That's taste, not texture)

Yes but do not expect to have crunch you get from breeding with it.

Yes, especially if you are using regular meat instead of lean; and if you are adding an egg to the mix.

Yes.